關於「RNA polymerase proofreading」標籤，搜尋引擎有相關的訊息討論：

RNA polymerase II transcriptional fidelity control and its functional ...。

RNA Polymerase II (Pol II) is the central enzyme responsible for pre-mRNA and ... During the proofreading step (step 3), cleavage of the RNA transcript ...。

Proofreading exonuclease activity of human DNA polymerase δ and ...。

Replicative DNA polymerases possess 3′ → 5′ exonuclease activity to reduce misincorporation of incorrect nucleotides by proofreading during replication.： tw | tw。

SARS-CoV-2 RdRp is a versatile enzyme with proofreading activity ...。

2021年11月17日 · The causative agent, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) employs the viral RNA-dependent RNA polymerase (RdRp) ...。

unique intra-molecular fidelity-modulating mechanism identified in a ...。

2018年9月20日 · Abstract. Typically not assisted by proofreading, the RNA-dependent RNA polymerases (RdRPs) encoded by the RNA viruses may need to ...。

Structure of the human RNA polymerase I elongation complex - Nature。

2021年10月20日 · Eukaryotic RNA polymerase I (Pol I) transcribes ribosomal DNA and ... sights into human Pol I complex organization and efficient proofreading.。

A recurrent cancer-associated substitution in DNA polymerase ε ...。

2019年1月22日 · First, mutations at catalytic residues in the exonuclease domain, which are well known to inactivate proofreading, are rarely or never seen in ...。

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The Fidelity of Human DNA Polymerase γ with and without ...。

The ability of pol γ both to make and to proofread dislocation intermediates is the first such evidence for a family A polymerase. Including the p55 accessory ...。

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is ...。

2018年3月6日 · Further, GS-5734 potently inhibits CoVs with intact proofreading. ... particularly the viral DNA or RNA polymerase (14), and have succeeded ...。

A New Model for the Regulation of RNA Virus Replication Fidelity。

2013年12月5日 · CoVs Encode a Proofreading 3′-to-5′ Exoribonuclease Distinct from the Viral RNA-Dependent RNA Polymerase. RNA viruses rely primarily on ...